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Asylum Research



MFP - 3D - BIO TM
AFM - Atomic Force Microscope

The Only Full-Capability AFM on an Inverted Optical Microscope.

The MFP - 3D - BIO sets the industry standard for combining optical and atomic force microscopies in a single integrated tool specifically designed for biologists.

Optical Integration; High Resolution Imaging; Quantitative Force Measurements; Environmental Controls;



Leadership in Force Spectroscopy and Force Mechanics:
- Simple setup, calibration, acquisition, display and analysis (any chanel vs. any chanel) with easy customization for advanced users.
- Superior 8pm deflectio noise (typical), 20 pm guaranteed.
- Accurate force measurements with no additional hardware required.
- Users can choose between open loop sensored force curves for the ultimate in low noise performance, or closed loop force curves for the most accurate velocity control.
- MacroBuilderTM graphical macro language allows custom force measurements to be easily programmed, even by beginners.
- Large vertical Z range (15µm standart, 40µm available) accommodates demanding applications  such as adhesion measurements on cells and very soft gels.
- Force Mapping enables mechanical measurements at a grid of points with automated extraction of material properties such as elastic modulus.
- Force Clamping for single-molecule and bond-rupture force spectroscopy measures unfolding or rupture kinetics under constant force, allowing direct comparison to theoretical models.
- Perpendicular drive, flexured nanoindenter (optional) provides accurate force and displacement control with superior resolution, sensitivity and precision.

All of the following optical microscopy techniques are supported:
1. Brightfield
2. Phase Contrast
3. Epifluorescence
4. Confocal Laser Scanning
5. TIRF
6. FRET
7. FCS
8. FRAP
9. Ion Indicators (e.g. Ca2+ response)

And the MFP - 3D's exclusive X-Y scanned-sample design is essential and enabling for:
- Apertureless Near-field Microscopy (ANSOM)
- Raman and Tip-enhanced Raman Spectroscopy
- Tip-enchanced Fluorescence
- Fluorescence Lifetime Imaging (FLIM) 



CYPHER - Scanning Probe Microscope.
Decoding the Nanoworld.



Choose the Cypher AFM for:
1. Closed-loop imaging from tens of microns down to atomic scales;
2. Small cantilevers for high-speed scanning;
3. High-speed, low-noise force measurements;
4. High-bandwidth data acquisition;
5. Diffraction-limited optical sample viewing/imaging;
6. Automated laser alignment.

Choose MFP-3D AFM for:
1. Large closed loop scan area;
2. Compatibility with inverted optical microscopes;
3. Sample viewing from top and bottom;
4. Long-range, low-noise force measurements;
5. Widest range of accessories;
6. Flexible mounting for various sample shapes and sizes;
7. Quantitative nanoindentation.